Cisplatin hyponatremia

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August undefined, 2024

WebApr 27, 2024 · Hyponatremia is a common adverse effect induced by cisplatin. Caution should be exercised with patients with a low sodium level before starting chemotherapy. … WebCisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome. A treatment strategy that incorporates both water restrictions and sodium supplementation may be appropriate when differentiating between diagnoses of renal salt wasting syndrome and syndrome of inappropriate antidiuretic hormone secretion.

Risk Factors for Severe Hyponatremia Related to Cisplatin: …

http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf WebMar 24, 2024 · Hyponatremia has been a recognized complication of platinum-based chemotherapy for decades. 7,8 There is limited data to quantify the overall incidence of … grain bin drying floor

Profound hyponatremia and dehydration: A case of cisplatin …

WebWe report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated … WebNational Center for Biotechnology Information WebJul 7, 2024 · 1 Department of Pharmacy, Showa University Hospital, Tokyo, Japan. 2 Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan. 3 Department of Surgery, Division of General and Gastroenterological Surgery, School of Medicine, Showa University, Tokyo, Japan. 4 Showa University Esophageal … china lending to bosnia

Renal Salt-Wasting Syndrome in a Patient With Cisplatin-Indu

WebSep 1, 2024 · Cisplatin for injection has been administered at 20 mg/m 2 intravenously daily for 5 days per cycle. Other doses and combination regimens have been used. ... other electrolyte abnormalities (hypocalcemia, hyponatremia, hypokalemia, and hypophosphatemia), Syndrome of Inappropriate Antidiuretic Hormone Excretion … WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignancies. 1,2 Approximately 20% of all cancer patients are … china lemon treeWebNov 21, 2024 · Cisplatin probably causes hyponatremia by causing SIADH and through its effect on the kidneys. ( 5 Trusted Source A Review of Drug-induced Hyponatremia Go to source) Painkillers: Opiates,... grain bin fan heaters

"WebMay 17, 2024 · Hyponatremia occurs when the concentration of sodium in your blood is abnormally low. Sodium is an electrolyte, and it helps regulate the amount of water that's … " - Cisplatin hyponatremia

Cisplatin hyponatremia

Cancer therapy-induced hyponatremia: A case-illustrated review

WebDec 3, 2014 · We retrospectively investigated the incidence of hyponatremia in patients receiving brand-name cisplatin (CDDP) and a generic counterpart thereof. Methods: We … Webmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less.

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WebJul 22, 2024 · Cisplatin-induced kidney toxicity is reviewed here. The use of cisplatin in patients with pre-existing kidney dysfunction and the kidney effects of the platinum … WebMar 15, 2024 · For patients who are unable to receive cisplatin due to medical frailty or comorbidities, options include a carboplatin-based regimen ( carboplatin plus gemcitabine, or carboplatin, gemcitabine, and paclitaxel) or a non-platinum-based combination (eg, paclitaxel plus gemcitabine) or even monotherapy (eg, gemcitabine).

WebAug 18, 2024 · Water losses from brain cells cause neurologic symptoms. Volume expansion and dilutional hyponatremia, without neurologic symptoms, can also be induced when isotonic mannitol is used as a flushing solution during transurethral resection of the prostate or bladder. WebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated …

Webhyponatremia was reported in 15% and 30.7% of 79 patients receiving brand and generic cisplatin respectively [16]. In our larger cisplatin treated cohort (n=298), all degree hyponatremia and moderate to severe hyponatremia was observed in 14.1% and 10% of patients respectively. In line with previous reports, hyponatremia was also WebFeb 16, 2024 · Cisplatin Dosage Medically reviewed by Drugs.com. Last updated on Feb 16, 2024. Applies to the following strengths: 50 mg; 10 mg; 1 mg/mL Usual Adult Dose for: Testicular Cancer Ovarian Cancer Bladder Cancer Usual Pediatric Dose for: Testicular Cancer Ovarian Cancer Bladder Cancer Additional dosage information: Renal Dose …

WebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia. * hypomagnesemia. …

WebProfound hyponatremia and dehydration: A case of cisplatin induced renal salt wasting syndrome 1 INTRODUCTION. Cis-diamminedichloroplatinum (CDDP), commonly known … grain bin fanWebSep 15, 2024 · SIDE EFFECTS. Nephrotoxicity - Dose-related and cumulative renal insufficiency is the major dose-limiting toxicity of cis-platin.Renal toxicity has been noted in 28% to 36% of patients treated with a single dose of 50 mg/m 2.It is first noted during the second week after a dose and is manifested by elevations in BUN and creatinine, serum … china lending money to countriesWebDec 20, 2024 · Background: Hyponatremia is a common electrolyte abnormality in cancer patients who receive chemotherapy. Among anticancer agents, platinum-based agents are reported to cause chemotherapy-induced hyponatremia. However, the actual incidence and risk factors remain unknown. Results: The reports of 29 trials were analyzed. grain bin fans and heatersWebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … china lens cleaning wipesWebJan 1, 2024 · Hyponatremia in cancer patients can be caused by a number of factors including gastrointestinal losses, cardiac failure, diabetes insipidus, cancer-induced … grain bin fans 12 inchWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. china lens cloth bulkWebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are common side effects of platinum … china length