Csf2ra

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WebDiseases associated with CSF2RA include surfactant metabolism dysfunction, pulmonary 4, and csf2ra-related pulmonary surfactant metabolism dysfunction. Description. CSF2RA … WebSome diseases are frequently found in the population and can be managed through drug and lifestyle therapies. An excellent example of this would be asthma. Other rarer diseases that may be present through a pulmonary genomics panel could include chronic respiratory disorders that affect airways, lung parenchyma, and vasculature.

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WebColony stimulating factor 2 receptor alpha, low-affinity (granulocyte-macrophage). CD116 molecule. Back to the top. Specifications Human CSF2RA isoform_1 (pUNO1-hCSF2RAa) Genbank: NM_006140.4 with one silent variation in codon Val333 ORF size: 1203 bp Subclone: AgeI - NheI . WebDec 3, 2015 · CSF2RA expression also reduced the stemness of RUNX1-ETO bone marrow cells and inhibited their colony forming ability. To identify which region of the receptor was mediating these pro-apoptotic effects, we generated truncation mutants and determined that the 25 amino acids at the carboxyl-terminus of the intracellular domain of CSF2RA are … higher power wiki

CSF2RB - an overview ScienceDirect Topics

WebMar 9, 2024 · Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder caused by recessive mutations in GM-CSF receptor subunit α/β genes (CSF2RA/CSF2RB, respectively) characterized by impaired GM-CSF-dependent surfactant clearance by alveolar macrophages (AMs) resulting in alveolar surfactant accumulation and … WebDec 1, 2024 · To facilitate the translation of PMT therapy to human hPAP patients, a self-inactivating (SIN) lentiviral vector was generated expressing a codon-optimized human CSF2RA-cDNA driven from an EF1α short promoter (Lv.EFS.CSF2RA coop), and a series of nonclinical efficacy and safety studies were performed in cultured macrophage cell … WebMar 21, 2024 · Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric … how find the lcd

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Anti-CSF2RA (CD116) Antibodies Invitrogen - Thermo Fisher Scientific

WebThe colony stimulating factor 2 receptor alpha (Csf2ra) gene encodes GM-CSF receptor a (CD116) in mice. Defective GM-CSF receptor signaling results in abnormal development and functionality of WebApr 8, 2024 · As expected, Csf2ra-deficient fetal liver monocytes transduced with control RV gfp could not expand in culture (Figure 7, B and C). Notably, overexpression of Csf2ra in WT fetal liver monocytes also provided a slight growth advantage over nontransduced WT fetal liver monocytes in vitro (Figure 7, B and C). how find task manager windows 10WebHuman Gene CSF2RA (uc004cpp.2) Description: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 3, mRNA. RefSeq Summary (NM_172246): higher power wireless router

"WebLow affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of … " - Csf2ra

Csf2ra

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WebAntibodies that detect CSF2RA (CD116) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry … WebDec 3, 2015 · CSF2RA expression also reduced the stemness of RUNX1-ETO bone marrow cells and inhibited their colony forming ability. To identify which region of the receptor …

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WebMay 2, 2024 · The congenital form of pulmonary alveolar proteinosis due to colony stimulating factor 2 receptor alpha gene mutations is a rare disease with only a few … WebAug 18, 2009 · Using an expression cloning strategy, Gearing et al. (1989) isolated a cDNA encoding CSF2RA, which they called GMCSFR, from a human placenta cDNA library. …

WebThe granulocyte-macrophage colony-stimulating factor receptor also known as CD116 ( C luster of D ifferentiation 116 ), is a receptor for granulocyte-macrophage colony … WebJan 5, 2024 · Orthologous to human CSF2RA (colony stimulating factor 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2024] Other designations. granulocyte-macrophage colony-stimulating factor receptor subunit alpha, GM-CSF-R-alpha, GM-CSFRalpha, GMCSFR-alpha, GMR-alpha, colony stimulating factor 2 receptor …

Webcolony stimulating factor 2 receptor alpha subunit : Nomenclature updated to reflect human and mouse nomenclature: 1299863: APPROVED: 2016-01-20: Csf2ra : colony … WebApr 8, 2024 · Harnessing the potential of this approach for gene therapy, we restored a disrupted Csf2ra gene in fetal liver monocytes and demonstrated their capacity to develop into alveolar macrophages in vivo. Altogether, we provide a platform for generation of immature alveolar macrophage-like precursors amenable for genetic manipulation, which …

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WebObjective: The aim of this study was to evaluate the relationship between cytokine production, GM-CSF receptor (CSF2RA), and IL-1 receptor (IL1R2) expression in … how find tax id numberWebThe gene view histogram is a graphical view of mutations across CSF2RA. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. how find the scale factorWebThere is a very high volume of traffic coming from your site (IP address 40.79.131.210) as of Mon Apr 10 18:05:48 2024 (California time). So that other users get a fair share of our bandwidth, we are putting in a delay of 10.2 seconds before we service your request. higher power yoga trenton njWebJun 1, 2024 · To address the role of GM-CSF receptor signaling in the pathogenesis of chronic airway inflammation in vivo, we used Csf2ra −/− mice, which were transplanted … higher poynton railway stationWebAntibodies that detect CSF2RA (CD116) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target CSF2RA (CD116) in Human, Mouse and Rat samples. Our CSF2RA (CD116) monoclonal, polyclonal and recombinant monoclonal antibodies are … how find the molar massWebApr 13, 2024 · 构建重组asfv- cd2v缺失毒株可下调jak2-stat3信号通路，诱导细胞凋亡。酵母双杂交系统筛选发现病毒蛋白cd2v与宿主蛋白csf2ra互作（图c），csf2ra是存在于髓系细胞中造血受体超家族成员，具有上调jak2和stat3蛋白表达水平的功能。 higher poynton pubWebDescription: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 11, non-coding RNA. RefSeq Summary (NR_027760): higher poynton canal