WebOct 1, 2024 · OPT-302 (Opthea), an IVT administered biologic, blocks VEGF-C and VEGF-D, and has undergone clinical study in conjunction with IVT anti-VEGF-A therapy in neovascular AMD and DME. ... This study will evaluate the efficacy, safety, and pharmacokinetics of the Port Delivery System with ranibizumab in participants with diabetic macular edema ... WebSep 13, 2024 · Opthea previously announced positive results of improvements in BCVA and retinal swelling (central subfield thickness and sub-retinal fluid) in the Phase 1/2a study patients that included treatment naïve and prior-treated prior-treated patients, suggesting additional clinical benefit with more complete suppression of VEGF-A and VEGF-C/D.
Opthea : presents Ph1/2a wAMD data at Retina Society Meeting
WebFeb 17, 2024 · Clinically significant ocular disorders (other than neovascular AMD), which may interfere with assessment of BCVA, assessment of safety, or fundus imaging. Any … WebAug 23, 2024 · August 23, 2024. Singapore – August 23, 2024 – Cooley advised Opthea, a clinical-stage biopharmaceutical company developing novel therapies to treat highly prevalent and progressive retinal diseases, on its non-dilutive financing arrangement for up to $170 million with Launch Therapeutics (Launch Tx), a recently formed development … in-country value icv certificate
Opthea Completes Patient Dosing in Phase 2a DME Trial
WebJan 7, 2024 · MELBOURNE, Australia, Jan. 07, 2024 (GLOBE NEWSWIRE) -- Opthea Limited (ASX:OPT), a clinical stage biopharmaceutical company developing novel biologic therapies to treat eye diseases, has completed patient recruitment into the Company’s Phase 2a trial evaluating the safety and efficacy of OPT-302 administered in combination with … WebMar 30, 2024 · Opthea has also reported outcomes from an international, multi-centre, prospective, sham-controlled, double-masked, superiority study that enrolled 366 … WebOct 4, 2024 · Opthea is conducting ShORe and COAST as two concurrent global, multi‑center, double‑masked, sham‑controlled Phase 3 trials to assess the efficacy and safety of intravitreal 2.0 mg OPT‑302 in... in-crl01a