Tsc2 cst
WebAug 1, 2024 · AbstractTuberous sclerosis complex (TSC) is caused by mutations of either the TSC1 or TSC2 tumor suppressor gene. TSC causes tumors of the brain, heart, kidney, skin and lymphangioleiomyomatosis (LAM). Here we report that the TSC2 protein physically binds to high-density lipoprotein binding protein (HDLBP), also called vigilin, a core stress … WebDec 3, 2024 · Mutations in genes that encode components of tuberous sclerosis complex 2 (TSC2) are associated with tuberous sclerosis complex disease. TSC2 interacts with …
Tsc2 cst
Did you know?
WebJul 12, 2024 · Tuberous Sclerosis Complex (TSC) is caused by TSC1 or TSC2 mutations, resulting in hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1). … WebMay 1, 2024 · Germline or mosaic loss-of-function mutations in either TSC1 or TSC2 give rise to the pleiotropic genetic ... 2.7 mM KCl, 0.1% Tween-20) plus 5% normal goat serum (NGS; CST #5425) was used as a blocking solution for 1 h at room temperature. Primary antibodies, p(S235/236)S6 (CST #4858, 1:400), fast skeletal Myosin (Sigma #M4276 ...
WebMay 17, 2024 · Loss-of-function mutations in TSC1 or TSC2, but not TBC1D7, give rise to TSC, a pleiotropic disorder with aberrant ... CST #5425) was used as a blocking solution … WebMonoclonal Antibody for studying Raptor. Cited in 516 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously …
WebAug 24, 2012 · The tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 complex, which limits cell growth in response to poor growth conditions. Through … WebGlaciecola sp. kul10 es una bacteria que se encuentra en ambientes extremos como los glaciares y los océanos. Su capacidad para producir enzimas y compuestos bioactivos la hace de interés para la investigación en campos como la …
WebJun 28, 2024 · To evaluate the knockdown efficiency of siRNA-TSC2 at the level of TSC2, high glucose-cultured podocytes were transfected with three different siRNA-TSC2 sequences. After TSC2 siRNA treatment for 24 h, Western blot analysis showed that transfection of TSC2 siRNA-1, TSC2 siRNA-2, and TSC2 siRNA-3 significantly reduced the …
WebMar 21, 2024 · TSC2 (TSC Complex Subunit 2) is a Protein Coding gene. Diseases associated with TSC2 include Lymphangioleiomyomatosis and Focal Cortical Dysplasia, … ons cpi february 2022WebMutations in TSC2 can cause Lymphangioleiomyomatosis, a disease caused by the enlargement of tissue in the lungs, creating cysts and tumours and causing difficulty … ons cpih ratesWebMay 17, 2024 · Loss-of-function mutations in TSC1 or TSC2, but not TBC1D7, give rise to TSC, a pleiotropic disorder with aberrant ... CST #5425) was used as a blocking solution for 1 h at room temperature. Primary antibodies, p(S235/236)S6 (CST #4858, 1:400), fast skeletal Myosin (Sigma #M4276, 1:400), and slow skeletal Myosin (Abcam # ... in your spare time do you help your parentsWebThe tumor suppressor genes TSC1 and TSC2 encode hamartin and tuberin, respectively (2,3). Hamartin and tuberin form a functional complex and are involved in numerous ... ons cpi increaseWebSep 18, 2015 · In cells with basal wt p53 function, p53-dependent transcription supplies adequate levels of TSC2 and sestrin2 to regulate mTORC1 kinase activity; when cells lose p53 transcriptional activity, TSC2 and Sestrin2 levels are low, TSC2 binding at the lysosomal sites of mTORC1 is low, Rheb levels are higher at these sites, and PRAS40 is lower in … ons cpi inflation datesWebPolyclonal Antibody for studying Tuberin/TSC2 (Ser1387) phosphate. Cited in 52 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. … ons cpi inflation rate ukWebFeb 23, 2024 · HDAC6 deacetylates TSC2 to sustain protein stability and associates with G3BP2 to facilitate more ... CST), Rheb (1:100; 13879, CST), G3BP2 (1:500; 16276-1-AP, … ons cpi methodology